The Effects Hormones Have on Your Mood

The Effects Hormones Have on Your Mood

Hormones are powerful chemicals that help keep our bodies working normally. The term hormone is derived from the Greek word, hormo, which means to set in motion. And that’s precisely what hormones do in the body. They stimulate, regulate, and control the function of various tissues and organs. Made by specialized groups of cells within structures called glands, hormones are involved in almost every biological process including sexual reproduction, growth, metabolism, and immune function. These glands, including the pituitary, thyroid, adrenals, ovaries and testes, release various hormones into the body as needed.

Neurotransmitters directly or indirectly control virtually every system in the body. The levels and balance of hormones are influenced by a number of important neurotransmitters. When neurotransmitters are out of balance from stress, poor diet, and genetic predisposition, the body can not maintain proper levels of key hormones. Neurotransmitter inbalance leads to or exacerbates hormone imbalance.Symptoms such as depression, mood swings, low libido, and lack of energy can occur in response to these fluctuating levels. Often, addressing neurotransmitter imbalances can reduce or correct hormonal imbalances by optimized communication between the brain and hormone producing glands.

Estrogen and Mood

Estrogens effect on mood is due to it’s ability to increase serotonin, and beta-endorphins which are associated with positive mood states, as well as acetylcholine your memory neurotransmitter. Estrogens are neuroprotective by encouraging the formation of new synapses in the brain, increasing the number of 5 HT2a receptors and increasing brain derived growth factor. It helps maintain serotonin, dopamine, and norepinephrine levels by decreasing levels of monoamine oxidase (MAO) the enzyme responsible for the inactivating them.

There have been research studies that have shown an association between decreased levels of estrogen and panic attacks. Many women may develop symptoms of depression, anxiety, and mood swings as estrogen levels begin to fluctuate during perimenopausal years then further decline at menopause. Too many women that suffer from menopause and depression have been put on anti-depressant medications instead of addressing the hormone levels through testing and natural bio identical hormones.

Symptoms of low estrogen:

  • Foggy Mind
  • Hot Flashes
  • Depression
  • Memory Lapses
  • Headaches
  • Vaginal Dryness
  • Irregular Periods
  • Urine Leakage
  • Sleep Problems
  • Bone Loss

Just as low Estrogen levels can wreak havoc with your system, high levels (estrogen dominance) can cause many symptoms as well. Instead of estrogen playing its essential role within the well-balanced system of steroid hormones, it has begun to overshadow the other players, creating biochemical imbalance. A major contributing factor to the imbalance between estrogen and progesterone is the increased exposure to pesticides, herbicides, plastics, and PCB’s. Estrogen dominance may be caused by normal levels of estrogen and relatively low levels of progesterone, or by low levels of estrogen and extremely low levels of progesterone.

Symptoms of too much estrogen:

  • Heavy Bleeding
  • Breast Tenderness
  • Increased premenstrual symptoms
  • Fibrocystic Breasts
  • Ovarian Cyst
  • Abdominal weight
  • Anxiety, Irritability
  • Water Retention
  • Increased Triglyceride Levels
  • Progesterone

Progesterone plays a key role in reproduction. Beyond preparation for pregnancy, progesterone has a multitude of effects throughout the body, many of which can be attributed to its ability to oppose the action of estrogen. Multiple physical and psychological problems at midlife are often caused by an imbalance between progesterone and estrogen.

The brain is highly responsive to progesterone. In fact, progesterone concentrations in the brain have been shown to be 20 times higher than in the blood. Insomnia, anxiety, and migraine are just a few of the conditions linked to an imbalance of progesterone and estrogen. In the brain as elsewhere in the body, progesterone counterbalances the effects of estrogen. Whereas estrogen has an excitatory effect on the brain, progesterone’s effect is calming. Clinical and anecdotal experience indicates that women with estrogen dominance sleep restlessly, whereas progesterone replenishment enhances sleep.


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